The Effect of Isokinectic Exercise on Biofluid Matrices as Measured by 1H NMR Spectroscopy
Lyons, Alexander 2015. The Effect of Isokinectic Exercise on Biofluid Matrices as Measured by 1H NMR Spectroscopy. PhD Thesis University of East London Health, Sport and Bioscience https://doi.org/10.15123/PUB.4772
The biochemical basis of muscle function during stress imposed by isokinetic exercise has mainly focused on measuring muscle proteins (CK and myoglobin) and lactate present in the blood plasma, whereas the range of low-molecular weight metabolites during muscular stress has received limited attention. This study investigated the effect of concentric isokinetic exercise of the knee extensor and flexor muscles (functional to standing, walking and running), at 80% and 40%MVC intensities of equal workloads, on saliva, urine and blood serum matrices. A hypothesis-free approach was employed to mathematically determine, by chemometrics, which untargeted metabolites measured by 1H NMR spectroscopy are altered in response to muscular exercise of this nature.
|Digital Object Identifier (DOI)||https://doi.org/10.15123/PUB.4772|
|Publication process dates|
|Deposited||01 Feb 2016|
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