Dr Tony Raynham
Name | Dr Tony Raynham |
---|---|
Job title | Senior Lecturer |
Email address | traynham@uel.ac.uk |
Research institute | Health, Sport & Bioscience |
Research outputs
Molecular basis of USP7 inhibition by selective small-molecule inhibitors
Turnbull, Andrew P., Ioannidis, Stephanos, Krajewski, Wojciech W., Pinto-Fernandez, Adan, Heride, Claire, Martin, Agnes C. L., Tonkin, Louise M., Townsend, Elizabeth C., Buker, Shane M., Lancia, David R., Caravella, Justin A., Toms, Angela V., Charlton, Thomas M., Lahdenranta, Johanna, Wilker, Erik, Follows, Bruce C., Evans, Nicola J., Stead, Lucy, Alli, Cristina, Zarayskiy, Vladislav V., Talbot, Adam C., Buckmelter, Alexandre J., Wang, Minghua, McKinnon, Crystal L., Saab, Fabienne, McGouran, Joanna F., Century, Hannah, Gersch, Malte, Pittman, Marc S., Marshall, C. Gary, Raynham, T., Simcox, Mary, Stewart, Lorna M. D., McLoughlin, Sheila B., Escobedo, Jaime A., Bair, Kenneth W., Dinsmore, Christopher J., Hammonds, Tim R., Kim, Sunkyu, Urbé, Sylvie, Clague, Michael J., Kessler, Benedikt M. and Komander, David 2017. Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature. 550 (7677), pp. 481-486. https://doi.org/10.1038/nature24451Investigation of the Role of Protein Kinase D in Human Rhinovirus Replication
Guedán, Anabel, Swieboda, Dawid, Charles, Mark, Toussaint, Marie, Johnston, Sebastian L., Asfor, Amin, Panjwani, Anusha, Tuthill, Tobias J., Danahay, Henry, Raynham, T., Mousnier, Aurelie, Solari, Roberto and Pfeiffer, Julie K. 2017. Investigation of the Role of Protein Kinase D in Human Rhinovirus Replication. Journal of Virology. 91 (9), pp. e00217-17. https://doi.org/10.1128/JVI.00217-17Discovery of potent inhibitors of the lysophospholipase autotaxin
Shah, Pritom, Cheasty, Anne, Foxton, Caroline, Raynham, T., Farooq, Muddasar, Gutierrez, Irene Farre, Lejeune, Aurore, Pritchard, Michelle, Turnbull, Andrew, Pang, Leon, Owen, Paul, Boyd, Susan, Stowell, Alexandra, Jordan, Allan, Hamilton, Niall M., Hitchin, James R., Stockley, Martin, MacDonald, Ellen, Quesada, Mar Jimenez, Trivier, Elisabeth, Skeete, Jana, Ovaa, Huib, Moolenaar, Wouter H. and Ryder, Hamish 2016. Discovery of potent inhibitors of the lysophospholipase autotaxin. Bioorganic & Medicinal Chemistry Letters. 26 (22), pp. 5403-5410. https://doi.org/10.1016/j.bmcl.2016.10.036Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase (AKR1C3)
Flanagan, Jack U., Atwell, Graham J., Heinrich, Daniel M., Brooke, Darby G., Silva, Shevan, Rigoreau, Laurent J.M., Trivier, Elisabeth, Turnbull, Andrew P., Raynham, T., Jamieson, Stephen M.F. and Denny, William A. 2014. Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase (AKR1C3). Bioorganic & Medicinal Chemistry. 22 (3), pp. 967-977. https://doi.org/10.1016/j.bmc.2013.12.050Protein kinase D2 regulates migration and invasion of U87MG glioblastoma cells in vitro
Bernhart, Eva, Damm, Sabine, Wintersperger, Andrea, DeVaney, Trevor, Zimmer, Andreas, Raynham, T., Ireson, Christopher and Sattler, Wolfgang 2013. Protein kinase D2 regulates migration and invasion of U87MG glioblastoma cells in vitro. Experimental Cell Research. 319 (13), pp. 2037-2048. https://doi.org/10.1016/j.yexcr.2013.03.029856
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