Fungal toenail infections
Ferrari, J. 2014. Fungal toenail infections. BMJ Clinical Evidence. 1715.
INTRODUCTION: Fungal infections are reported to cause 23% of foot diseases and 50% of nail conditions in people seen by dermatologists, but are less common in the general population, affecting 3% to 12% of people. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of oral treatments for fungal toenail infections in adults? What are the effects of topical treatments for fungal toenail infections in adults? We searched: Medline, Embase, The Cochrane Library, and other important databases up to October 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). RESULTS: We found 13 studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. CONCLUSIONS: In this systematic review, we present information relating to the effectiveness and safety of the following interventions: amorolfine, butenafine, ciclopirox, fluconazole, itraconazole, terbinafine, tioconazole, and topical ketoconazole.
|Journal||BMJ Clinical Evidence|
|Publisher||BMJ Publishing Group|
|Web address (URL)||http://clinicalevidence.bmj.com/x/systematic-review/1715/overview.html|
|Online||13 Mar 2014|
|Publication process dates|
|Deposited||22 Jan 2018|
|Copyright information||© 2014 BMJ Publishing Group Ltd|
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