Modelling the adverse effects associated with ecstasy use

Article


Fisk, John E., Murphy, Philip N., Montgomery, Catharine and Hadjiefthyvoulou, F. 2010. Modelling the adverse effects associated with ecstasy use. Addiction. 106 (4), pp. 798-805.
AuthorsFisk, John E., Murphy, Philip N., Montgomery, Catharine and Hadjiefthyvoulou, F.
Abstract

Aims  Ecstasy, the street name for 3,4‐meththylenedioxymethamphetamine, has been associated with a range of psychiatric symptoms and impaired psychological health in both problem and recreational users. The purpose of the present paper is to determine how these impairments are related to the history of polydrug use, and the conditions under which individuals ingest ecstasy.

Design  Associations between the variables of interest were investigated utilizing negative binomial regression.

Setting  Liverpool and Preston in the North West of England.

Participants  A convenience sample of 159 recreational ecstasy/polydrug users (80 males, 79 females). The sample was composed primarily of undergraduates.

Measurements  The dependent variable was the number of reported ecstasy‐related adverse effects. Independent variables included quantitative aspects of ecstasy and other drug use, and the various beliefs and behaviours associated with ecstasy use.

Findings  The number of adverse effects was associated positively with life‐time exposure to ecstasy and negatively with period of abstinence from the drug. Adverse effects were more common among those who consumed ecstasy and alcohol concurrently, but were unrelated to other aspects of polydrug use. They were unaffected by whether the user took precautions when using the drug, and only weakly related to prior beliefs concerning the effects of ecstasy.

Conclusions  Greater life‐time exposure to ecstasy and consuming the drug concurrently with alcohol increase the likelihood of experiencing adverse effects, including paranoia, poor general health, irritability, confusion and moodiness. Adverse effects decrease with the period of abstinence from the drug.

JournalAddiction
Journal citation106 (4), pp. 798-805
ISSN0965-2140
Year2010
PublisherWiley
Accepted author manuscript
Digital Object Identifier (DOI)doi:10.1111/j.1360-0443.2010.03272.x
Web address (URL)https://doi.org/10.1111/j.1360-0443.2010.03272.x
Publication dates
Online29 Oct 2010
Publication process dates
Deposited07 Nov 2018
Accepted21 Oct 2010
Accepted21 Oct 2010
Copyright information© 2010 The Authors, Addiction © 2010 Society for the Study of Addiction. This is the peer reviewed version of the following article: Fisk, J. E., Murphy, P. N., Montgomery, C. and Hadjiefthyvoulou, F. 'Modelling the adverse effects associated with ecstasy use', Addiction, 106, pp.798-805, which has been published in final form at https://doi.org/10.1111/j.1360-0443.2010.03272.x. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
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