Nucleotide supplementation: a randomised double-blind placebo controlled trial of IntestAidIB in people with Irritable Bowel Syndrome [ISRCTN67764449]
Dancey, C., Attree, E. and Brown, K.F. 2006. Nucleotide supplementation: a randomised double-blind placebo controlled trial of IntestAidIB in people with Irritable Bowel Syndrome [ISRCTN67764449]. Nutrition Journal.
|Authors||Dancey, C., Attree, E. and Brown, K.F.|
Work with infants has shown that the incidence and duration of diarrhoea is lower when nucleotide supplementation is given, and animal work shows that villi height and crypt depth in the intestine is increased as a result of dietary nucleotides. Dietary nucleotides may be semi-essential under conditions of ill-health, poor diet or stress. Since people with Irritable Bowel Syndrome tend to fulfil these conditions, we tested the hypothesis that symptoms would be improved with dietary nucleotide supplementation on thirty-seven people with a diagnosis of Irritable Bowel.
|Keywords||IBS; Irritable Bowel Syndrome; nucleotide supplementation; stress; dietary health; placebo condition; psychological measures; depression; health anxiety|
|Web address (URL)||http://hdl.handle.net/10552/239|
|08 Jun 2006|
|Publication process dates|
|Deposited||07 Aug 2009|
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