José Ignacio Saldaña


NameJosé Ignacio Saldaña
Email addressJ.I.Saldana@uel.ac.uk

Research outputs

Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation

Lau, Ching-In, Yánez, Diana C., Solanki, Anisha, Papaioannou, Eleftheria, Saldaña, J. and Crompton, Tessa 2018. Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation. Journal of Autoimmunity. 93, pp. 131-138. https://doi.org/10.1016/j.jaut.2018.07.009

Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of Shh

Solanki, Anisha, Yanez, Diana C., Ross, Susan, Lau, Ching-In, Papaioannou, Eleftheria, Li, Jiawei, Saldaña, J. and Crompton, Tessa 2018. Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of Shh. Development. 145 (3), p. dev146910. https://doi.org/10.1242/dev.146910

The transcription factor Gli3 promotes B cell development in fetal liver through repression of Shh

Solanki, Anisha, Lau, Ching-In, Saldaña, J., Ross, Susan and Crompton, Tessa 2017. The transcription factor Gli3 promotes B cell development in fetal liver through repression of Shh. The Journal of Experimental Medicine. 214 (7), pp. 2041 -2058. https://doi.org/10.1084/jem.20160852

The kinesin motor protein Kif7 is required for T-cell development and normal MHC expression on thymic epithelial cells (TEC) in the thymus

Lau, Ching-In, Barbarulo, Alessandro, Solanki, Anisha, Saldaña, J. and Crompton, Tessa 2017. The kinesin motor protein Kif7 is required for T-cell development and normal MHC expression on thymic epithelial cells (TEC) in the thymus. Oncotarget. 8 (15), pp. 24163-24176. https://doi.org/10.18632/oncotarget.15241

Hedgehog Signalling in the Embryonic Mouse Thymus

Barbarulo, A., Lau, C-I., Mengrelis, K., Ross, S., Solanki, A., Saldaña, J. and Crompton, T. 2016. Hedgehog Signalling in the Embryonic Mouse Thymus. Journal of Developmental Biology. 4 (3), p. 22. https://doi.org/10.3390/jdb4030022

Sonic Hedgehog regulates thymic epithelial cell differentiation

Saldaña, J., Solanki, Anisha, Lau, Ching-In, Sahni, Hemant, Ross, Susan, Furmanski, Anna L., Ono, Masahiro, Holländer, Georg and Crompton, Tessa 2016. Sonic Hedgehog regulates thymic epithelial cell differentiation. Journal of Autoimmunity. 68 (April), pp. 86-97. https://doi.org/10.1016/j.jaut.2015.12.004

A genome wide transcriptional model of the complex response to pre-TCR signalling during thymocyte differentiation

Sahni, Hemant, Susan, Ross, Barbarulo, Alessandro, Solanki, Anisha, Lau, Ching-In, Furmanski, Anna, Saldaña, J., Ono, Masahiro, Hubank, Mike, Barenco, Martino and Crompton, Tessa 2015. A genome wide transcriptional model of the complex response to pre-TCR signalling during thymocyte differentiation. Oncotarget. 6 (30), pp. 28646-28660. https://doi.org/10.18632/oncotarget.5796
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