The interpersonal adverse effects reported by 1008 users of antidepressants; and the incremental impact of polypharmacy
Read, J., Gee, Aimee, Diggle, Jacob and Butler, Helen 2017. The interpersonal adverse effects reported by 1008 users of antidepressants; and the incremental impact of polypharmacy. Psychiatry Research. 256, pp. 423-427.
|Authors||Read, J., Gee, Aimee, Diggle, Jacob and Butler, Helen|
Antidepressant drugs are being prescribed at ever increasing rates internationally, despite marginal benefit compared to placebo and a range of adverse effects. Most studies of adverse effects focus on biological phenomena. This article presents the results of an online survey of 1008 self-selected anti-depressant users in Britain, which asked about five adverse effects in the interpersonal domain. The most commonly reported among participants who took only antidepressants were: Sex Life – 43.7%, Work or Study – 27.0% and Social Life – 23.5%. These rates of interpersonal adverse effects were even higher for the 52% of participants who were also taking one or more other psychiatric drugs. Only about a half (48%) felt they had been given enough information about side effects by the prescriber. Those initially prescribed medication by a psychiatrist were more likely to be on several types of drugs and reported more adverse effects than those whose prescriber was a General Practitioner (GP). Researchers and prescribers are encouraged to pay greater attention to interpersonal adverse effects.
|Journal citation||256, pp. 423-427|
|Accepted author manuscript|
|Digital Object Identifier (DOI)||doi:10.1016/j.psychres.2017.07.003|
|Web address (URL)||https://doi.org/10.1016/j.psychres.2017.07.003|
|03 Jul 2017|
|Publication process dates|
|Deposited||31 Jul 2017|
|Accepted||02 Jul 2017|
|Copyright information||© 2017 Elsevier|
|License||CC BY-NC-ND 3.0|
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