Developmental outcomes of 3,4-methylenedioxymethamphetamine (ecstasy)-exposed infants in the UK

Article


Singer, Lynn T., Moore, Derek G., Min, Meeyoung O., Goodwin, Julia, Turner, J., Fulton, Sarah and Parrott, Andrew C. 2015. Developmental outcomes of 3,4-methylenedioxymethamphetamine (ecstasy)-exposed infants in the UK. Human Psychopharmacology: Clinical and Experimental. 30 (4), pp. 290-294.
AuthorsSinger, Lynn T., Moore, Derek G., Min, Meeyoung O., Goodwin, Julia, Turner, J., Fulton, Sarah and Parrott, Andrew C.
Abstract

Objective—This paper aims to review findings from a longitudinal study of prenatal methylenedioxymethamphetamine (MDMA, “ecstasy”) on infant development.
Methods—In a prospective, longitudinal cohort design, we followed 28 MDMA-exposed and 68 non-MDMA-exposed infants from birth to 2 years of age. Women recruited voluntarily into a study of recreational drug use during pregnancy were interviewed to obtain type, frequency, and amount of recreational drug use. Their children were followed for a 2-year period after birth. A large number of drug and environmental covariates were controlled. Infants were seen at 1, 4, 12, 18, and 24 months using standardized normative tests of mental and motor development.
Results—There were no differences between MDMA-exposed and non-MDMA-exposed infants at birth except that MDMA-exposed infants were more likely to be male. Motor delays were evident in MDMA infants at each age and amount of MDMA exposure predicted motor deficits at 12 months in a dose-dependent fashion.
Conclusions—Prenatal MDMA exposure is related to fine and gross motor delays in the first 2 years of life. Follow-up studies are needed to determine long-term effects.

JournalHuman Psychopharmacology: Clinical and Experimental
Journal citation30 (4), pp. 290-294
ISSN08856222
Year2015
PublisherWiley
Digital Object Identifier (DOI)doi:10.1002/hup.2459
Web address (URL)https://doi.org/10.1002/hup.2459
Publication dates
Online28 Jul 2015
Publication process dates
Deposited01 Aug 2018
Accepted05 Dec 2014
Accepted05 Dec 2014
FunderNational Institute on Drug Abuse
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https://repository.uel.ac.uk/item/85545

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