Psychiatric profiles of mothers who take Ecstasy/MDMA during pregnancy: Reduced depression 1 year after giving birth and quitting Ecstasy

Article

Turner, J., Parrott, Andrew C, Goodwin, Julia, Moore, Derek G, Fulton, Sarah, Min, Meeyoung O and Singer, Lynn T 2014. Psychiatric profiles of mothers who take Ecstasy/MDMA during pregnancy: Reduced depression 1 year after giving birth and quitting Ecstasy. Journal of Psychopharmacology. 28 (1), pp. 55-61. https://doi.org/10.1177/0269881113515061
AuthorsTurner, J., Parrott, Andrew C, Goodwin, Julia, Moore, Derek G, Fulton, Sarah, Min, Meeyoung O and Singer, Lynn T
Abstract

Background:

The recreational drug MDMA (3,4-methylenedioxymethamphetamine) or ‘Ecstasy’ is associated with heightened psychiatric distress and feelings of depression. The Drugs and Infancy Study (DAISY) monitored the psychiatric symptom profiles of mothers who used Ecstasy/MDMA while pregnant, and followed them over the first year post-partum.
Methods:

We compared 28 young women whom took MDMA during their pregnancy with a polydrug control group of 68 women who took other psychoactive drugs while pregnant. The Brief Symptom Inventory (BSI) was completed for several periods: The first trimester of pregnancy; and 1, 4 and 12 months after childbirth. Recreational drug use was monitored at each time point.
Results:

During the first trimester of pregnancy, MDMA-using mothers reported higher depression scores than the polydrug controls. At 1 year after childbirth, their BSI depression scores were significantly lower, now closer to the control group values. At the same time point, their self-reported use of MDMA became nearly zero, in contrast to their continued use of Cannabis/marijuana, nicotine and alcohol. We found significant symptom reductions in those with BSI obsessive-compulsive and interpersonal sensitivity, following Ecstasy/MDMA cessation.
Conclusions:

The findings from this unique prospective study of young recreational drug-using mothers are consistent with previous reports of improved psychiatric health after quitting MDMA.

JournalJournal of Psychopharmacology
Journal citation28 (1), pp. 55-61
ISSN0269-8811
Year2014
PublisherSAGE Publications for British Association for Psychopharmacology
Accepted author manuscript
Digital Object Identifier (DOI)https://doi.org/10.1177/0269881113515061
Web address (URL)https://doi.org/10.1177/0269881113515061
Publication dates
Online10 Dec 2013
Print01 Jan 2014
Publication process dates
Deposited31 Jul 2018
FunderNational Institute on Drug Abuse in America
Copyright informationTurner, John J.D. and Parrott, Andrew C and Goodwin, Julia and Moore, Derek G and Fulton, Sarah and Min, Meeyoung O and Singer, Lynn T (2014) ‘Psychiatric profiles of mothers who take Ecstasy/MDMA during pregnancy: Reduced depression 1 year after giving birth and quitting Ecstasy’, Journal of Psychopharmacology, 28(1), pp. 55-61. Copyright © 2013 SAGE Publications. Reprinted by permission of SAGE Publications.
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