Cochrane Qualitative and Implementation Methods Group Guidance series - paper 6: Methods for question formulation, searching and protocol development for qualitative evidence synthesis

Article

Harris, Janet L., Booth, Andrew, Cargo, Margaret, Hannes, Karin, Harden, A., Flemming, Kate, Garside, Ruth, Pantoja, Tomas, Thomas, James and Noyes, Jane 2018. Cochrane Qualitative and Implementation Methods Group Guidance series - paper 6: Methods for question formulation, searching and protocol development for qualitative evidence synthesis. Journal of Clinical Epidemiology. 97, pp. 39-48. https://doi.org/10.1016/j.jclinepi.2017.10.023
AuthorsHarris, Janet L., Booth, Andrew, Cargo, Margaret, Hannes, Karin, Harden, A., Flemming, Kate, Garside, Ruth, Pantoja, Tomas, Thomas, James and Noyes, Jane
Abstract

This paper updates previous Cochrane guidance on question formulation,searching and protocol development, reflecting recent developments in methods for conducting qualitative evidence syntheses to inform Cochrane intervention reviews. Examples are used to illustrate how decisions about boundaries for a review are formed via an iterative process of constructing lines of inquiry, and mapping the information available to ascertain whether evidence exists to answer questions related to effectiveness, implementation, feasibility, appropriateness, economic evidence, and equity. The process of question formulation allows reviewers to situate the topic in relation to how it informs and explains effectiveness, using the criterion of meaningfulness, appropriateness, feasibility and implementation. Questions related to complex questions and interventions can be structured by drawing on an increasingly wide range of question frameworks. Logic models and theoretical frameworks are useful tools for conceptually mapping the literature to illustrate the complexity of the phenomenon of interest. Further, protocol development may require iterative question formulation and searching. Consequently, the final protocol may function as a guide rather than a prescriptive route-map, particularly in qualitative reviews that ask more exploratory and open ended questions.

JournalJournal of Clinical Epidemiology
Journal citation97, pp. 39-48
ISSN0895-4356
Year2018
PublisherElsevier
Accepted author manuscript
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Digital Object Identifier (DOI)https://doi.org/10.1016/j.jclinepi.2017.10.023
Web address (URL)https://doi.org/10.1016/j.jclinepi.2017.10.023
Publication dates
Online15 Dec 2017
PrintMay 2018
Publication process dates
Deposited05 Jan 2018
Accepted17 Oct 2017
Accepted17 Oct 2017
Copyright information© 2017 Elsevier
Additional information

This Accepted Manuscript states it is paper 6 in the series: the Version of Record is paper 2.

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