Dr Samir Ayoub


NameDr Samir Ayoub
Job titleSenior Lecturer
Email addresss.s.ayoub@uel.ac.uk
Research instituteHealth, Sport & Bioscience

Research outputs

Paracetamol (acetaminophen): A familiar drug with an unexplained mechanism of action

Ayoub, S. S. 2021. Paracetamol (acetaminophen): A familiar drug with an unexplained mechanism of action. Temperature. 8 (4), pp. 351-371. https://doi.org/10.1080/23328940.2021.1886392

Effects of heparan sulfates with different structures on leukaemia cells: U937 and THP-1 cell differentiation

Bajwa, P., Garrido Mesa, N., Seed, M. and Ayoub, S. 2019. Effects of heparan sulfates with different structures on leukaemia cells: U937 and THP-1 cell differentiation. 14th World Congress on Inflammation 2019. Sydney, AU 15 - 19 Sep 2019 World Congress on Inflammation.

Sucrose octasulphate regulates the expression of M1 and M2 macrophage-specific markers in U937 monocytes

Bajwa, P., Garrido Mesa, N., Seed, M. and Ayoub, S. 2019. Sucrose octasulphate regulates the expression of M1 and M2 macrophage-specific markers in U937 monocytes. 14th World Congress on Inflammation 2019. Sydney, AU 15 - 19 Sep 2019 World Congress on Inflammation.

Loss of hypothermic and anti-pyretic action of paracetamol in cyclooxygenase-1 knockout mice is indicative of inhibition of cyclooxygenase-1 variant enzymes

Ayoub, S. and Flower, R. J. 2019. Loss of hypothermic and anti-pyretic action of paracetamol in cyclooxygenase-1 knockout mice is indicative of inhibition of cyclooxygenase-1 variant enzymes. European Journal of Pharmacology. 861 (Art. 172609). https://doi.org/10.1016/j.ejphar.2019.172609

Pharmacological targeting of the GABAʙ receptor alters Drosophila's behavioural responses to alcohol

Ranson, D., Ayoub, S., Corcoran, O. and Casalotti, S. 2019. Pharmacological targeting of the GABAʙ receptor alters Drosophila's behavioural responses to alcohol. Addiction Biology. 25 (Art. e12725). https://doi.org/10.1111/adb.12725

Role of GABAB receptors in ethanol induced behaviours

Ranson, D., Ayoub, S. and Casalotti, S. 2017. Role of GABAB receptors in ethanol induced behaviours. pA2 Online: Proceedings of the British Pharmacological Society. 18 (1).

Pharmacological Modulation of Alcohol Tolerance via GABA-B receptors in Drosophila melanogaster

Ranson, D., Ayoub, S., Corcoran, O. and Casalotti, S. 2018. Pharmacological Modulation of Alcohol Tolerance via GABA-B receptors in Drosophila melanogaster. 11th FENS Forum of Neuroscience. Berlin, Germany 07 - 11 Jul 2018

Naltrexone Reverses Ethanol Preference and Protein Kinase C Activation in Drosophila melanogaster

Koyyada, Rajeswari, Latchooman, Nilesh, Jonaitis, Julius, Ayoub, S., Corcoran, O. and Casalotti, S. 2018. Naltrexone Reverses Ethanol Preference and Protein Kinase C Activation in Drosophila melanogaster. Frontiers in Physiology. 9 (175), pp. 1-7. https://doi.org/10.3389/fphys.2018.00175

The perception of Pharmacology among undergraduate students at the University of East London

Deshai, Devyani and Ayoub, S. 2017. The perception of Pharmacology among undergraduate students at the University of East London. Pharmacology 2017. Queen Elizabeth II Conference Centre, London, UK 11 - 13 Dec 2017

First evidence of the conversion of paracetamol to AM404 in human cerebrospinal fluid

Sharma,, Chhaya V., Long, Jamie H., Shah, Seema, Rahman, Junia, Perrett, David, Ayoub, S. and Mehta, Vivek 2017. First evidence of the conversion of paracetamol to AM404 in human cerebrospinal fluid. Pharmacology 2017. Queen Elizabeth II Conference Centre, London, UK 11 - 13 Dec 2017

The requirement of p38-MAPKinase and peroxisome proliferator-activated receptor-g for the induction of cyclooxygenase-2 by interleukin-4 drives macrophages into an anti-inflammatory phenotype

Manoj, Sivanjaa, Morgan, W. and Ayoub, S. 2017. The requirement of p38-MAPKinase and peroxisome proliferator-activated receptor-g for the induction of cyclooxygenase-2 by interleukin-4 drives macrophages into an anti-inflammatory phenotype. Pharmacology 2017. Queen Elizabeth II Conference Centre, London, UK 11 - 13 Dec 2017

First evidence of the conversion of paracetamol to AM404 in human cerebrospinal fluid

Sharma, Chhaya, Long, Jamie H, Shah, Seema, Rahman, Junia, Perrett, David, Ayoub, S. and Mehta, Vivek 2017. First evidence of the conversion of paracetamol to AM404 in human cerebrospinal fluid. Journal of Pain Research. 10, pp. 2703-2709. https://doi.org/10.2147/JPR.S143500

Role of gamma-aminobutyric acid-B receptors in ethanol induced behaviours

Ranson, D., Ayoub, S. and Casalotti, S. 2017. Role of gamma-aminobutyric acid-B receptors in ethanol induced behaviours. Society for the Study of Addiction Conference. Newcastle, UK 08 - 10 Nov 2017

Construction of cell models for drug-receptor pharmacology activities for schools outreach: Generating awareness and interest in pharmacology in the younger generations

Ayoub, S., Cooper, Chelsey, Nunes, Fernando and Ruocco, Ray 2016. Construction of cell models for drug-receptor pharmacology activities for schools outreach: Generating awareness and interest in pharmacology in the younger generations. Pharmacology 2015. Queen Elizabeth Conference Centre, London 15 - 17 Dec 2015 pA2 Online British Pharmacological Society.

Characterisation of the signalling mechanisms involved in the induction of cyclooxygenase-2 by interleukin-4

Sivanjaa Manoj, Manoj, Morgan, W. and Ayoub, S. 2016. Characterisation of the signalling mechanisms involved in the induction of cyclooxygenase-2 by interleukin-4. PHARMACOLOGY 2016. The Queen Elizabeth II Conference Centre, London 13 - 15 Dec 2016 London British Pharmacological Society.

New and novel uses for paracetamol

Ayoub, S. 2013. New and novel uses for paracetamol. UEL Research and Knowledge Exchange Conference 2013. University of East London, London 26 Jun 2013 London University of East London.
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