Does RecA have a role in Borrelia recurrentis?
Cutler, S., Rinky, I. J. and Bonilla, E. M. 2011. Does RecA have a role in Borrelia recurrentis? Clinical Microbiology and Infection. 17 (2), pp. 195-197.
|Authors||Cutler, S., Rinky, I. J. and Bonilla, E. M.|
Genomic sequencing of two relapsing fever spirochaetes showed truncation of recA in Borrelia recurrentis, but not in Borrelia duttonii. RecA has an important role among bacteria; we investigated whether this characteristic was representative of B. recurrentis, or an artefact following in vitro cultivation. We sequenced recA directly from samples of patient with louse-borne relapsing fever (B. recurrentis) or tick-borne relapsing fever (B. duttonii). We confirmed the premature stop codon in seven louse-borne relapsing fever samples, and its absence from three tick-borne relapsing fever samples. Furthermore, specific signature polymorphisms were found that could differentiate between these highly similar spirochaetes.
|Journal||Clinical Microbiology and Infection|
|Journal citation||17 (2), pp. 195-197|
|Publisher||Elsevier for European Society of Clinical Microbiology and Infectious Diseases|
|Web address (URL)||http://dx.doi.org/10.1111/j.1469-0691.2010.03249.x|
|Publication process dates|
|Deposited||16 Dec 2014|
|Copyright information||© The Authors. Available under a Creative Commons Attribution Non-Commercial No Derivatives 3.0 Unported License.|
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