Does RecA have a role in Borrelia recurrentis?

Article

Cutler, S., Rinky, I. J. and Bonilla, E. M. 2011. Does RecA have a role in Borrelia recurrentis? Clinical Microbiology and Infection. 17 (2), pp. 195-197.
AuthorsCutler, S., Rinky, I. J. and Bonilla, E. M.
Abstract

Genomic sequencing of two relapsing fever spirochaetes showed truncation of recA in Borrelia recurrentis, but not in Borrelia duttonii. RecA has an important role among bacteria; we investigated whether this characteristic was representative of B. recurrentis, or an artefact following in vitro cultivation. We sequenced recA directly from samples of patient with louse-borne relapsing fever (B. recurrentis) or tick-borne relapsing fever (B. duttonii). We confirmed the premature stop codon in seven louse-borne relapsing fever samples, and its absence from three tick-borne relapsing fever samples. Furthermore, specific signature polymorphisms were found that could differentiate between these highly similar spirochaetes.

JournalClinical Microbiology and Infection
Journal citation17 (2), pp. 195-197
ISSN1198743X
Year2011
PublisherElsevier for European Society of Clinical Microbiology and Infectious Diseases
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CC BY-NC-ND
Publisher's version
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CC BY-NC-ND
Publisher's version
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Web address (URL)http://dx.doi.org/10.1111/j.1469-0691.2010.03249.x
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PrintFeb 2011
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Deposited16 Dec 2014
Copyright information© The Authors. Available under a Creative Commons Attribution Non-Commercial No Derivatives 3.0 Unported License.
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