Application of computational methods in isolation of plant secondary metabolites

Book chapter

Rahman, M. 2018. Application of computational methods in isolation of plant secondary metabolites. in: Sarker, S. and Nahar, L. (ed.) Computational Phytochemistry Elsevier.

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Authors	Rahman, M.
Editors	Sarker, S. and Nahar, L.
Abstract	Plant-derived secondary metabolites have made great contributions to today’s medicine. Separation and purification of such metabolites from a complex mixture are sometimes quite challenging. The incorporation of computational methods in chromatography has facilitated the separation of compounds from a complex mixture. Such techniques are automatic, robust, and offer efficient separation of secondary metabolites. This chapter highlights the computer-aided techniques associated with automated flash chromatography, high-performance/pressure liquid chromatography (HPLC), ultra-pressure/performance liquid chromatography (UPLC), ion-exchange chromatography, counter current chromatography, and capillary electrophoresis for the isolation of secondary metabolites. Hyphenated techniques, such as GC-MS, LC-MS, and LC-NMR, have also been included for natural product isolation and identification. Several examples of isolation of plant-derived secondary metabolites using computer-aided chromatographic methods are incorporated.
Book title	Computational Phytochemistry
Year	2018
Publisher	Elsevier
Print	01 May 2018
Publication process dates
Deposited	01 Dec 2017
ISBN	9780128123645
Web address (URL)	https://www.elsevier.com/books/computational-phytochemistry/sarker/978-0-12-812364-5

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