Application of computational methods in isolation of plant secondary metabolites

Book chapter

Rahman, M. 2018. Application of computational methods in isolation of plant secondary metabolites. in: Sarker, Satyajit and Nahar, Lutfun (ed.) Computational Phytochemistry Elsevier.

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Authors	Rahman, M.
Editors	Sarker, Satyajit and Nahar, Lutfun
Abstract	Plant - derived secondary metabolites have made great contribution s to today’s medicine. Separation and purification of such metabolites from a complex mixture are sometime s quite challenging. The incorporation of computational methods in chromatography has facilitated the separation of compounds from a complex mixtu re. Such techniques are automatic, robust and offer efficient separa tion of secondary metabolites . This chapter highlights the computer - aided techniques associated with automated flash chromatography, HPLC, UPLC, i on exchange chromatography, counter current chromatography and c apillary electrophoresis for the isolation of secondary metabolites. Hyphenated techniques , such as GC - MS, LC - MS and L C - NMR , have also been included for natural product isolation and identification. S everal examples of isolation of plant - derived secon dary metabolites using computer - aided chromatographic methods are incorporated .
Book title	Computational Phytochemistry
Year	2018
Publisher	Elsevier
Print	01 May 2018
Publication process dates
Deposited	01 Dec 2017
ISBN	9780128123645
Web address (URL)	https://www.elsevier.com/books/computational-phytochemistry/sarker/978-0-12-812364-5

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