Antibacterial constituents of Neohyptis paniculata

Article


Rahman, M. and Gibbons, Simon 2015. Antibacterial constituents of Neohyptis paniculata. Fitoterapia. 105, pp. 269-272.
AuthorsRahman, M. and Gibbons, Simon
Abstract

A new -pyrone, 6R-[5R,6S-diacetyloxy-1Z,3E-heptadienyl]-5,6-dihydro-2H-pyran-2one (1), along with six known compounds including an α-pyrone, flavones and terpenes was isolated from the aerial parts of Neohyptis paniculata. The structure of 1 was established unambiguously by MS and a series of 1D and 2D-NMR spectroscopic analyses. The antibacterial activity of the compounds (1-7) was investigated against five strains of multi-drug resistant (MDR) and methicillin-resistant Staphylococcus aureus and minimum inhibitory concentrations (MICs) of these compounds were found to be in the range of 64-256 g/mL.

JournalFitoterapia
Journal citation105, pp. 269-272
ISSN0367326X
Year2015
PublisherElsevier
Accepted author manuscript
License
CC BY-NC-ND
Web address (URL)http://dx.doi.org/10.1016/j.fitote.2015.07.012
Publication dates
Print21 Jul 2015
Publication process dates
Deposited27 Jul 2015
Accepted09 Jul 2015
FunderLeverhulme Trust
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