Antibacterial constituents of Neohyptis paniculata

Article


Rahman, M. and Gibbons, Simon 2015. Antibacterial constituents of Neohyptis paniculata. Fitoterapia. 105, pp. 269-272.
AuthorsRahman, M. and Gibbons, Simon
Abstract

A new -pyrone, 6R-[5R,6S-diacetyloxy-1Z,3E-heptadienyl]-5,6-dihydro-2H-pyran-2one (1), along with six known compounds including an α-pyrone, flavones and terpenes was isolated from the aerial parts of Neohyptis paniculata. The structure of 1 was established unambiguously by MS and a series of 1D and 2D-NMR spectroscopic analyses. The antibacterial activity of the compounds (1-7) was investigated against five strains of multi-drug resistant (MDR) and methicillin-resistant Staphylococcus aureus and minimum inhibitory concentrations (MICs) of these compounds were found to be in the range of 64-256 g/mL.

JournalFitoterapia
Journal citation105, pp. 269-272
ISSN0367326X
Year2015
PublisherElsevier
Accepted author manuscript
License
CC BY-NC-ND
Web address (URL)http://dx.doi.org/10.1016/j.fitote.2015.07.012
Publication dates
Print21 Jul 2015
Publication process dates
Deposited27 Jul 2015
Accepted09 Jul 2015
FunderLeverhulme Trust
Permalink -

https://repository.uel.ac.uk/item/85557

  • 3
    total views
  • 9
    total downloads
  • 1
    views this month
  • 4
    downloads this month

Related outputs

Terpenes from Zingiber montanum and Their Screening against Multi-Drug Resistant and Methicillin Resistant Staphylococcus aureus
Siddique, H., Pendry, B. and Rahman, M. 2019. Terpenes from Zingiber montanum and Their Screening against Multi-Drug Resistant and Methicillin Resistant Staphylococcus aureus. Molecules. 24 (3), p. Art. 385.
Total synthesis of acylphloroglucinols and their antibacterial activities against clinical isolates of multi-drug resistant (MDR) and methicillin-resistant strains of Staphylococcus aureus
Rahman, M., Shiu, Winnie K.P., Gibbons, Simon and Malkinson, John P. 2018. Total synthesis of acylphloroglucinols and their antibacterial activities against clinical isolates of multi-drug resistant (MDR) and methicillin-resistant strains of Staphylococcus aureus. European Journal of Medicinal Chemistry. 155, pp. 255-262.
Antimicrobial Secondary Metabolites—Extraction, Isolation, Identification, and Bioassay
Rahman, M. 2015. Antimicrobial Secondary Metabolites—Extraction, Isolation, Identification, and Bioassay. in: Evidence-Based Validation of Herbal Medicine Elsevier. pp. 495-513
Anti-Staphylococcal Calopins from Fruiting Bodies of Caloboletus radicans
Tareq, Fakir Shahidullah, Hasan, Choudhury Mahmood, Rahman, M., Hanafi, Mohd Murkish Mohd, Ciacchi, Lucio Colombi, Michaelis, Monika, Harder, Tilmann, Tebben, Jan, Islam, Md. Tofazzal and Spiteller, Peter 2018. Anti-Staphylococcal Calopins from Fruiting Bodies of Caloboletus radicans. Journal of Natural Products. 81 (2), pp. 400-404.
Analogues of Disulfides from Allium stipitatum Demonstrate Potent Anti-tubercular Activities through Drug Efflux Pump and Biofilm Inhibition
Danquah, Cynthia A., Kakagianni, Eleftheria, Khondkar, Proma, Maitra, Arundhati, Rahman, M., Evangelopoulos, Dimitrios, McHugh, Timothy D., Stapleton, Paul, Malkinson, John, Bhakta, Sanjib and Gibbons, Simon 2018. Analogues of Disulfides from Allium stipitatum Demonstrate Potent Anti-tubercular Activities through Drug Efflux Pump and Biofilm Inhibition. Scientific Reports. 8 (1150).
Application of computational methods in isolation of plant secondary metabolites
Rahman, M. 2018. Application of computational methods in isolation of plant secondary metabolites. in: Sarker, Satyajit and Nahar, Lutfun (ed.) Computational Phytochemistry Elsevier.
Anti-MRSA Activity of Oxysporone and Xylitol from the Endophytic Fungus Pestalotia sp. Growing on the Sundarbans Mangrove Plant Heritiera fomes
Nurunnabi, Tauhidur Rahman, Nahar, Lutfun, Al-Majmaie, Shaymaa, Mahbubur Rahman, S. M., Sohrab, Md. Hossain, Billah, Md. Morsaline, Ismail, Fyaz M.D., Rahman, M., Sharples, George P. and Sarker, Satyajit D. 2017. Anti-MRSA Activity of Oxysporone and Xylitol from the Endophytic Fungus Pestalotia sp. Growing on the Sundarbans Mangrove Plant Heritiera fomes. Phytotherapy Research. 32 (2), pp. 348-354.
Antimicrobial resistance and synergy in herbal medicine
Mundy, Lorna, Pendry, Barbara and Rahman, M. 2016. Antimicrobial resistance and synergy in herbal medicine. Journal of Herbal Medicine. 6 (2), pp. 53-58.
Conversion of salvianolic acid B into salvianolic acid A in tissues of Radix Salviae Miltiorrhizae using high temperature, high pressure and high humidity
Xia, Hongrui, Sun, Longru, Lou, Hongxiang and Rahman, M. 2014. Conversion of salvianolic acid B into salvianolic acid A in tissues of Radix Salviae Miltiorrhizae using high temperature, high pressure and high humidity. Phytomedicine.