Prof Cynthia Fu


NameProf Cynthia Fu
ORCIDhttps://orcid.org/0000-0003-4313-3500
Job titleProfessor
Email addressc.fu@uel.ac.uk
Research institutePsychology
Research outputs

Research outputs

Comparative efficacy and acceptability of non-surgical brain stimulation for the acute treatment of major depressive episodes in adults: systematic review and network meta-analysis

Mutz, Julian, Vipulananthan, Vijeinika, Carter, Ben, Hurlemann, René, Fu, C. and Young, Allan H. 2019. Comparative efficacy and acceptability of non-surgical brain stimulation for the acute treatment of major depressive episodes in adults: systematic review and network meta-analysis. BMJ. 364, p. Art. l1079.

Anodal transcranial direct current stimulation over the right dorsolateral prefrontal cortex enhances reflective judgment & decision-making

Edgcumbe, Daniel R., Thoma, V., Rivolta, Davide, Nitsche, Michael A. and Fu, C. 2018. Anodal transcranial direct current stimulation over the right dorsolateral prefrontal cortex enhances reflective judgment & decision-making. Brain Stimulation. 12 (3), pp. 652-658.

Associations between polygenic risk scores for four psychiatric illnesses and brain structure using multivariate pattern recognition

Ranlund, Siri, Rosa, Maria Joao, de Jong, Simone, Cole, James H., Kyriakopoulos, Marinos, Fu, C., Mehta, Mitul A. and Dima, Danai 2018. Associations between polygenic risk scores for four psychiatric illnesses and brain structure using multivariate pattern recognition. NeuroImage: Clinical. 20, pp. 1026-1036.

Unravelling the GSK3β-related genotypic interaction network influencing hippocampal volume in recurrent major depressive disorder

Inkster, Becky, Simmons, Andy, Cole, James, Schoof, Erwin, Linding, Rune, Nichols, Tom, Muglia, Pierandrea, Holsboer, Florian, Saemann, Philipp, McGuffin, Peter, Fu, C., Miskowiak, Kamilla, Matthews, Paul M., Zai, Gwyneth and Nicodemus, Kristin 2018. Unravelling the GSK3β-related genotypic interaction network influencing hippocampal volume in recurrent major depressive disorder. Psychiatric Genetics. 28 (5), pp. 77-84.

A systematic review and meta-analysis of the neural correlates of psychological therapies in major depression

Sankar, Anjali, Melin, Alice, Lorenzetti, Valentina, Horton, Paul, Costafreda, Sergi G. and Fu, C. 2018. A systematic review and meta-analysis of the neural correlates of psychological therapies in major depression. Psychiatry Research: Neuroimaging. 279, pp. 31-39.

Efficacy and acceptability of non-invasive brain stimulation for the treatment of adult unipolar and bipolar depression: A systematic review and meta-analysis of randomised sham-controlled trials

Mutz, Julian, Edgcumbe, Daniel R., Brunoni, Andre R. and Fu, C. 2018. Efficacy and acceptability of non-invasive brain stimulation for the treatment of adult unipolar and bipolar depression: A systematic review and meta-analysis of randomised sham-controlled trials. Neuroscience & Biobehavioral Reviews. 92, pp. 291-303.

Other race effect on amygdala response during affective facial processing in major depression

Sankar, Anjali, Costafreda, Sergi G., Marangell, Lauren B. and Fu, C. 2018. Other race effect on amygdala response during affective facial processing in major depression. Neuroscience Letters. 662, pp. 381-384.

A systematic review of the neurophysiology of mindfulness on EEG oscillations

Lomas, T., Ivtzan, I. and Fu, C. 2015. A systematic review of the neurophysiology of mindfulness on EEG oscillations. Neuroscience & Biobehavioral Reviews. 57, pp. 401-410.

Multimodal functional and structural neuroimaging investigation of major depressive disorder following treatment with duloxetine

Fu, C., Costafreda, Sergi G, Sankar, Anjali, Adams, Tracey M, Rasenick, Mark M, Liu, Peng, Donati, Robert, Maglanoc, Luigi A, Horton, Paul and Marangell, Lauren B 2015. Multimodal functional and structural neuroimaging investigation of major depressive disorder following treatment with duloxetine. BMC Psychiatry. 15 (1).

Meta-analyses of structural regional cerebral effects in type 1 and type 2 diabetes

Moulton, Calum D., Costafreda, Sergi G., Horton, Paul, Ismail, Khalida and Fu, C. 2015. Meta-analyses of structural regional cerebral effects in type 1 and type 2 diabetes. Brain Imaging and Behavior. 9 (4), pp. 651-662.

Neural effects of cognitive–behavioural therapy on dysfunctional attitudes in depression

Sankar, A., Scott, J., Paszkiewicz, A., Giampietro, V. P., Steiner, H. and Fu, C. 2014. Neural effects of cognitive–behavioural therapy on dysfunctional attitudes in depression. Psychological Medicine. 45 (7), pp. 1425-1433.

Hippocampal atrophy in first episode depression: A meta-analysis of magnetic resonance imaging studies

Cole, James, Costafreda, Sergi G., McGuffin, Peter and Fu, C. 2011. Hippocampal atrophy in first episode depression: A meta-analysis of magnetic resonance imaging studies. Journal of Affective Disorders. 134 (1-3), pp. 483-487.

Pattern of neural responses to verbal fluency shows diagnostic specificity for schizophrenia and bipolar disorder

Costafreda, Sergi G, Fu, C., Picchioni, Marco, Toulopoulou, Timothea, McDonald, Colm, Kravariti, Eugenia, Walshe, Muriel, Prata, Diana, Murray, Robin M and McGuire, Philip K 2011. Pattern of neural responses to verbal fluency shows diagnostic specificity for schizophrenia and bipolar disorder. BMC Psychiatry. 11 (1), p. 18.

Amygdala activation to masked happy facial expressions

Juruena, Mario F., Giampietro, Vincent P., Smith, Stephen D., Surguladze, Simon A., Dalton, Jeffrey A., Benson, Philip J., Cleare, Anthony J. and Fu, C. 2010. Amygdala activation to masked happy facial expressions. Journal of the International Neuropsychological Society. 16 (02), pp. 383-387.

Prognostic and Diagnostic Potential of the Structural Neuroanatomy of Depression

Domschke, Katharina, Costafreda, Sergi G., Chu, Carlton, Ashburner, John and Fu, C. 2009. Prognostic and Diagnostic Potential of the Structural Neuroanatomy of Depression. PLOS ONE. 4 (7), p. e6353.

Neural basis of the emotional Stroop interference effect in major depression

Mitterschiffthaler, M. T., Williams, S. C. R., Walsh, N. D., Cleare, A. J., Donaldson, C., Scott, J. and Fu, C. 2008. Neural basis of the emotional Stroop interference effect in major depression. Psychological Medicine. 38 (02), pp. 247-256.

Brain-derived neurotrophic factor association with amygdala response in major depressive disorder

Lorenzetti, V., Costafreda, S. G., Rimmer, R., Rasenick, M. M., Marangell, L. B. and Fu, C. 2020. Brain-derived neurotrophic factor association with amygdala response in major depressive disorder. Journal of Affective Disorders. 267, pp. 103-106.

The Neuroscience of Sadness: A Multidisciplinary Synthesis and Collaborative Review for the Human Affectome Project

Arias, J. A., Williams, C., Raghvani, R., Aghajani, M., Baez, S., Belzung, C., Booij, L., Busatto, G., Chiarella, J., Fu, C., Ibanez, A., Liddell, B. J., Lowe, L., Penninx, B. W. J. H., Rosa, P. and Kemp, A. H. 2020. The Neuroscience of Sadness: A Multidisciplinary Synthesis and Collaborative Review for the Human Affectome Project. Neuroscience & Biobehavioral Reviews. 111, pp. 199-228.

Addressing heterogeneity (and homogeneity) in treatment mechanisms in depression and the potential to develop diagnostic and predictive biomarkers

Fu, C., Fan, Y. and Davatzikos, C. 2019. Addressing heterogeneity (and homogeneity) in treatment mechanisms in depression and the potential to develop diagnostic and predictive biomarkers. NeuroImage: Clinical. 24 (Art.101997).

Predictors of amygdala activation during the processing of emotional stimuli: A meta-analysis of 385 PET and fMRI studies

Costafreda, Sergi G., Brammer, Michael J., David, Anthony S. and Fu, C. 2007. Predictors of amygdala activation during the processing of emotional stimuli: A meta-analysis of 385 PET and fMRI studies. Brain Research Reviews. 58 (1), pp. 57-70.

Pattern Classification of Sad Facial Processing: Toward the Development of Neurobiological Markers in Depression

Fu, C., Mourao-Miranda, Janaina, Costafreda, Sergi G., Khanna, Akash, Marquand, Andre F., Williams, Steve C.R. and Brammer, Michael J. 2008. Pattern Classification of Sad Facial Processing: Toward the Development of Neurobiological Markers in Depression. Biological Psychiatry. 63 (7), pp. 656-662.

Neural Responses to Sad Facial Expressions in Major Depression Following Cognitive Behavioral Therapy

Fu, C., Williams, Steven C.R., Cleare, Anthony J., Scott, Jan, Mitterschiffthaler, Martina T., Walsh, Nicholas D., Donaldson, Catherine, Suckling, John, Andrew, Chris, Steiner, Herbert and Murray, Robin M. 2008. Neural Responses to Sad Facial Expressions in Major Depression Following Cognitive Behavioral Therapy. Biological Psychiatry. 64 (6), pp. 505-512.

Neuroanatomy of verbal working memory as a diagnostic biomarker for depression

Marquand, Andre F., Mourão-Miranda, Janaina, Brammer, Michael J., Cleare, Anthony J. and Fu, C. 2008. Neuroanatomy of verbal working memory as a diagnostic biomarker for depression. NeuroReport. 19 (15), pp. 1507-1511.

Neural correlates of sad faces predict clinical remission to cognitive behavioural therapy in depression

Costafreda, Sergi G., Khanna, Akash, Mourao-Miranda, Janaina and Fu, C. 2009. Neural correlates of sad faces predict clinical remission to cognitive behavioural therapy in depression. NeuroReport. 20 (7), pp. 637-641.

Subregional hippocampal deformations in major depressive disorder

Cole, James, Toga, Arthur W., Hojatkashani, Cornelius, Thompson, Paul, Costafreda, Sergi G., Cleare, Anthony J., Williams, Steven C.R., Bullmore, Edward T., Scott, Jan L., Mitterschiffthaler, Martina T., Walsh, Nicholas D., Donaldson, Catherine, Mirza, Mubeena, Marquand, Andre, Nosarti, Chiara, McGuffin, Peter and Fu, C. 2010. Subregional hippocampal deformations in major depressive disorder. Journal of Affective Disorders. 126 (1-2), pp. 272-277.

Ketamine-Induced Disruption of Verbal Self-Monitoring Linked to Superior Temporal Activation

Stone, J. M., Abel, K. M., Allen, M.P.G., van Haren, N., Matsumoto, K., McGuire, P. K. and Fu, C. 2010. Ketamine-Induced Disruption of Verbal Self-Monitoring Linked to Superior Temporal Activation. Pharmacopsychiatry. 44 (1), pp. 33-48.

Machine learning classification with confidence: Application of transductive conformal predictors to MRI-based diagnostic and prognostic markers in depression

Nouretdinov, Ilia, Costafreda, Sergi G., Gammerman, Alexander, Chervonenkis, Alexey, Vovk, Vladimir, Vapnik, Vladimir and Fu, C. 2011. Machine learning classification with confidence: Application of transductive conformal predictors to MRI-based diagnostic and prognostic markers in depression. NeuroImage. 56 (2), pp. 809-813.

Cortisol responses to serial MRI scans in healthy adults and in depression

Peters, Sabine, Cleare, Anthony J., Papadopoulos, Andrew and Fu, C. 2011. Cortisol responses to serial MRI scans in healthy adults and in depression. Psychoneuroendocrinology. 36 (5), pp. 737-741.

No effect of 5HTTLPR or BDNF Val66Met polymorphism on hippocampal morphology in major depression

Cole, J., Weinberger, D. R., Mattay, V. S., Cheng, X., Toga, A. W., Thompson, P. M., Powell-Smith, G., Cohen-Woods, S., Simmons, A., McGuffin, P. and Fu, C. 2011. No effect of 5HTTLPR or BDNF Val66Met polymorphism on hippocampal morphology in major depression. Genes, Brain and Behavior. 10 (7), pp. 756-764.

Interaction between effects of genes coding for dopamine and glutamate transmission on striatal and parahippocampal function

Pauli, Andreina, Prata, Diana P., Mechelli, Andrea, Picchioni, Marco, Fu, C., Chaddock, Christopher A., Kane, Fergus, Kalidindi, Sridevi, McDonald, Colm, Kravariti, Eugenia, Toulopoulou, Timothea, Bramon, Elvira, Walshe, Muriel, Ehlert, Natascha, Georgiades, Anna, Murray, Robin, Collier, David A. and McGuire, Philip 2012. Interaction between effects of genes coding for dopamine and glutamate transmission on striatal and parahippocampal function. Human Brain Mapping. 34 (9), pp. 2244-2258.

White matter abnormalities and illness severity in major depressive disorder

Cole, James, Chaddock, Christopher A., Farmer, Anne E., Aitchison, Katherine J., Simmons, Andrew, McGuffin, Peter and Fu, C. 2012. White matter abnormalities and illness severity in major depressive disorder. British Journal of Psychiatry. 201 (01), pp. 33-39.

Predictive neural biomarkers of clinical response in depression: A meta-analysis of functional and structural neuroimaging studies of pharmacological and psychological therapies

Fu, C., Steiner, Herbert and Costafreda, Sergi G. 2013. Predictive neural biomarkers of clinical response in depression: A meta-analysis of functional and structural neuroimaging studies of pharmacological and psychological therapies. Neurobiology of Disease. 52, pp. 75-83.

Modulation of amygdala response and connectivity in depression by serotonin transporter polymorphism and diagnosis

Costafreda, Sergi G., McCann, Peter, Saker, Pascal, Cole, James H., Cohen-Woods, Sarah, Farmer, Anne E., Aitchison, Katherine J., McGuffin, Peter and Fu, C. 2013. Modulation of amygdala response and connectivity in depression by serotonin transporter polymorphism and diagnosis. Journal of Affective Disorders. 150 (1), pp. 96-103.

Body mass index, but not FTO genotype or major depressive disorder, influences brain structure

Cole, J.H., Boyle, C.P., Simmons, A., Cohen-Woods, S., Rivera, M., McGuffin, P., Thompson, P.M. and Fu, C. 2013. Body mass index, but not FTO genotype or major depressive disorder, influences brain structure. Neuroscience. 252 (Nov.), pp. 109-117.

Neuroimaging-Based Biomarkers in Psychiatry: Clinical Opportunities of a Paradigm Shift

Fu, C. and Costafreda, Sergi G. 2013. Neuroimaging-Based Biomarkers in Psychiatry: Clinical Opportunities of a Paradigm Shift. Canadian Journal of Psychiatry. 58 (9), pp. 499-508.

Modafinil Augmentation Therapy in Unipolar and Bipolar Depression

Goss, Alexander J., Kaser, Muzaffer, Costafreda, Sergi G., Sahakian, Barbara J. and Fu, C. 2013. Modafinil Augmentation Therapy in Unipolar and Bipolar Depression. The Journal of Clinical Psychiatry. 74 (11), pp. 1101-1107.

Recent Advances in Neuroimaging of Mood Disorders: Structural and Functional Neural Correlates of Depression, Changes with Therapy, and Potential for Clinical Biomarkers

Atkinson, Lauren, Sankar, Anjali, Adams, Tracey M. and Fu, C. 2014. Recent Advances in Neuroimaging of Mood Disorders: Structural and Functional Neural Correlates of Depression, Changes with Therapy, and Potential for Clinical Biomarkers. Current Treatment Options in Psychiatry. 1 (3), pp. 278-293.

Modulatory effects of brain-derived neurotrophic factor Val66Met polymorphism on prefrontal regions in major depressive disorder

Legge, R. M., Sendi, S., Cole, J. H., Cohen-Woods, S., Costafreda, S. G., Simmons, A., Farmer, A. E., Aitchison, K. J., McGuffin, P. and Fu, C. 2015. Modulatory effects of brain-derived neurotrophic factor Val66Met polymorphism on prefrontal regions in major depressive disorder. The British Journal of Psychiatry. 206 (5), pp. 379-384.

Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis

Wise, T., Radua, J., Via, E., Cardoner, N., Abe, O., Adams, T. M., Amico, F., Cheng, Y., Cole, J. H., de Azevedo Marques Périco, C., Dickstein, D. P., Farrow, T. F. D., Frodl, T., Wagner, G., Gotlib, I. H., Gruber, O., Ham, B. J., Job, D. E., Kempton, M. J., Kim, M. J., Koolschijn, P. C. M. P., Malhi, G. S., Mataix-Cols, D., McIntosh, A. M., Nugent, A. C., O'Brien, J. T.., Pezzoli, S, Phillips, M. L., Sachdev, P. S., Salvadore, G., Selvaraj, S., Stanfield, A. C., Thomas, A. J., van Tol, M. J., van der Wee, N. J. A., Veltman, D. J., Young, A. H., Fu, C., Cleare, A. J. and Arnone, D. 2016. Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis. Molecular Psychiatry.

Diagnostic potential of structural neuroimaging for depression from a multi-ethnic community sample

Sankar, Anjali, Zhang, Tianhao, Gaonkar, Bilwaj, Doshi, Jimit, Erus, Guray, Costafreda, Sergi G., Marangell, Lauren, Davatzikos, Christos and Fu, C. 2016. Diagnostic potential of structural neuroimaging for depression from a multi-ethnic community sample. BJPsych Open. 2 (4), pp. 247-254.

Effects of antidepressant therapy on neural components of verbal working memory in depression

Sankar, Anjali, Adams, Tracey M, Costafreda, Sergi G. and Fu, C. 2017. Effects of antidepressant therapy on neural components of verbal working memory in depression. Journal of Psychopharmacology. 31 (9), pp. 1176-1183.

Classification of Major Depressive Disorder via Multi-Site Weighted LASSO Model

Zhu, Dajiang, Riedel, Brandalyn C., Jahanshad, Neda, Groenewold, Nynke A., Stein, Dan J., Gotlib, Ian H., Dima, Danai, Cole, James H., Fu, C., Walter, Henrik, Veer, Ilya M., Frodl, Thomas, Schmaal, Lianne, Veltman, Dick J. and Thompson, Paul M. 2017. Classification of Major Depressive Disorder via Multi-Site Weighted LASSO Model. in: Descoteaux, Maxime, Maier-Hein, Lena, Franz, Alfred, Jannin, Pierre, Collins, D. Louis and Duchesne, Simon (ed.) Medical Image Computing and Computer-Assisted Intervention − MICCAI 2017 Springer, Cham.

The effect of psychosis associated CACNA1C, and its epistasis with ZNF804A, on brain function

Tecelão, Diogo, Mendes, Ana, Martins, Daniel, Fu, C., Chaddock, Christopher A, Picchioni, Marco M, McDonald, Colm, Kalidindi, Sridevi, Murray, Robin and Prata, Diana P 2018. The effect of psychosis associated CACNA1C, and its epistasis with ZNF804A, on brain function. Genes, Brain and Behavior. 18 (4), p. e12510.
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