Shorter spontaneous fixation durations in infants with later emerging autism

Article

Wass, S., Jones, Emily J. H., Gliga, Teodora, Smith, Tim J., Charman, Tony and Johnson, Mark H. 2015. Shorter spontaneous fixation durations in infants with later emerging autism. Scientific Reports. 5 (1), p. Art. 8284. https://doi.org/10.1038/srep08284
AuthorsWass, S., Jones, Emily J. H., Gliga, Teodora, Smith, Tim J., Charman, Tony and Johnson, Mark H.
Abstract

Little is known about how spontaneous attentional deployment differs on a millisecond-level scale in the early development of autism spectrum disorders (ASD). We measured fine-grained eye movement patterns in 6-to 9-month-old infants at high or low familial risk (HR/LR) of ASD while they viewed static images. We observed shorter fixation durations (i.e. the time interval between saccades) in HR than LR infants. Preliminary analyses indicate that these results were replicated in a second cohort of infants. Fixation durations were shortest in those infants who went on to receive an ASD diagnosis at 36 months. While these findings demonstrate early-developing atypicality in fine-grained measures of attentional deployment early in the etiology of ASD, the specificity of these effects to ASD remains to be determined.

JournalScientific Reports
Journal citation5 (1), p. Art. 8284
ISSN2045-2322
Year2015
PublisherNature Research
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Digital Object Identifier (DOI)https://doi.org/10.1038/srep08284
Web address (URL)https://doi.org/10.1038/srep08284
Publication dates
Online06 Feb 2015
Publication process dates
Deposited04 Dec 2018
Accepted12 Jan 2015
Accepted12 Jan 2015
FunderMedical Research Council
The BASIS Funding Consortium
Innovative Medicines Initiative
European Cooperation in Science
British Academy
Medical Research Council
BASIS Funding Consortium
Innovative Medicines Initiative
European Cooperation in Science and Technology
British Academy
Copyright information© 2015 The authors
LicenseCC BY 4.0
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