Shorter spontaneous fixation durations in infants with later emerging autism

Article

Wass, S., Jones, Emily J. H., Gliga, Teodora, Smith, Tim J., Charman, Tony and Johnson, Mark H. 2015. Shorter spontaneous fixation durations in infants with later emerging autism. Scientific Reports. 5 (1), p. Art. 8284. https://doi.org/10.1038/srep08284

Publication dates
Authors	Wass, S., Jones, Emily J. H., Gliga, Teodora, Smith, Tim J., Charman, Tony and Johnson, Mark H.
Abstract	Little is known about how spontaneous attentional deployment differs on a millisecond-level scale in the early development of autism spectrum disorders (ASD). We measured fine-grained eye movement patterns in 6-to 9-month-old infants at high or low familial risk (HR/LR) of ASD while they viewed static images. We observed shorter fixation durations (i.e. the time interval between saccades) in HR than LR infants. Preliminary analyses indicate that these results were replicated in a second cohort of infants. Fixation durations were shortest in those infants who went on to receive an ASD diagnosis at 36 months. While these findings demonstrate early-developing atypicality in fine-grained measures of attentional deployment early in the etiology of ASD, the specificity of these effects to ASD remains to be determined.
Journal	Scientific Reports
Journal citation	5 (1), p. Art. 8284
ISSN	2045-2322
Year	2015
Publisher	Nature Research
Publisher's version	srep08284.pdf License CC BY 4.0
Supplemental file	srep08284-s1.pdf License CC BY 4.0
Digital Object Identifier (DOI)	https://doi.org/10.1038/srep08284
Web address (URL)	https://doi.org/10.1038/srep08284
Online	06 Feb 2015
Publication process dates
Deposited	04 Dec 2018
Accepted	12 Jan 2015
Accepted	12 Jan 2015
Funder	Medical Research Council
	The BASIS Funding Consortium
	Innovative Medicines Initiative
	European Cooperation in Science
	British Academy
	Medical Research Council
	BASIS Funding Consortium
	Innovative Medicines Initiative
	European Cooperation in Science and Technology
	British Academy
Copyright information	© 2015 The authors
License	CC BY 4.0

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