Anglo-Saxon pharmacopoeia revisited: a potential treasure in drug discovery

Article

Watkins, Frances, Pendry, B., Corcoran, O. and Sanchez-Medina, Alberto 2011. Anglo-Saxon pharmacopoeia revisited: a potential treasure in drug discovery. Drug Discovery Today. 16 (23-24), pp. 1069-1075.
AuthorsWatkins, Frances, Pendry, B., Corcoran, O. and Sanchez-Medina, Alberto
Abstract

Three Anglo-Saxon manuscripts reporting medicinal formulations in England from the tenth century survive: the ‘Old English Herbarium’, Bald’s Leechbooks and ‘Lacnunga’ which may contain new leads and insights into new medicinal uses. Previous pharmacological studies of 16th and 17th century medicinal plants reported in the Anglo-Saxon medical texts, suggest some were effective and led to the identification and isolation of new natural compounds such as matricin from Achillea millefolium L., a prodrug that yields chamazulene carboxylic acid, a natural profen. New insights through multidisciplinary projects could further explore the manuscript content for the discovery of metabolites with potential pharmacological applications.

Keywordsherbal pharmacopoeia; British flora; drug discovery
JournalDrug Discovery Today
Journal citation16 (23-24), pp. 1069-1075
ISSN1359-6446
Year2011
PublisherElsevier
Web address (URL)http://dx.doi.org/10.1016/j.drudis.2011.07.002
Publication dates
PrintDec 2011
Publication process dates
Deposited30 Nov 2012
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